Along with collaborating with future Blair Witch cohorts Eduardo Sánchez and Gregg Hale on a trilogy of short films, Daniel Myrick supported himself by working as an editor and cinematographer on a number of Florida-based music videos and commercials. After he wrote and directed the promo for the Florida Film Festival in 1997, Myrick’s work caught the eye of independent film guru John Pierson, helping to set the stage for the eventual 1999 debut of Myrick and Sanchez’s first feature as co-writers and directors, The Blair Witch Project.  The film became a resounding box office success, grossing over $248 million worldwide against an estimated budget of $60,000, making it one of the most successful independent films of all time.

In 2006, he co-founded Raw Feed, a direct to DVD division of Warner Home Video that specializes in horror films, with The X-Files executive producer John Shiban and 24 executive producer Tony Krantz.

Most recently he wrote and directed Under the Bed which can be seen on the Lifetime Movie Network.