De Zarn’s best known for Spider-Man (2002) (playing Mary Jane Watson‘s father), Fight Club (1999), Live Free or Die Hard (2007), The Cabin in the Woods (2012), Untraceable (2008), and Demon Knight (1995). He has appeared in several American television series, including Dr. Quinn, Medicine Woman, NYPD Blue, the various Star Trek TV franchises, Prime Suspect, Mad Men, The Forgotten, Lost, Criminal Minds,Weeds, Prison Break, Deadwood, The Shield, Cold Case, Quantum Leap, and 7th Heaven.
De Zarn has been quoted as saying “the best part of acting is being something you’re not, so that’s why I play the bad guys. . . It’s just too much fun!” His first broadcast role was on the TV series The Equalizer in 1986. His first film role was in the 1989 action comedy Three Fugitives.